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Frieden was kicking at an open door: Bloomberg had been a 60-a-day smoker but was now on the road to Damascus

PGC-1 is the central molecule in mitochondrial biogenesis ( 3 COPD The World Health Organization (WHO) has reported that COPD caused 3.22 million deaths worldwide in 2019, which represents an increase of 17.5% from 2007 to 2017, the major burden of COPD deaths occurs in Latin America, sub-Saharan Africa, India, Southeast Asia, and China (Figure 1)

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